LIMZER
COMPOSITION :
Limzer
Each capsule contains :
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Omeprazole BP (as enteric coated pellets)
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20
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mg
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Domperidone BP (as sustained release pellets)
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30
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mg
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PRODUCT SOURCE
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: OUTSOURCED (THEMIS LABORATORIES PVT. LTD., (INDIA)
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CLINICAL PHARMACOLOGY :
Omeprazole is in a class of drugs called proton pump inhibitors (PPI) which block the production of acid by the stomach. Omeprazole is a, so-called substituted benzimidazoles, which must be activated by acid to inhibit the proton pump. Omeprazole is used for the treatment of conditions such as ulcers, gastroesophageal reflux disease (GERD) and the Zollinger-Ellison Syndrome which are all caused by stomach acid. It also is used in combination with antibiotics for eradicating H.pylori infection of the stomach.
Domperidone is a dopamine antagonist. It stimulates esophageal peristalsis, increases LESP, and accelerates gastric emptying.
INDICATION AND DOSAGE:
Enteric Coated Omeprazole and Domperidone SR Capsules combines Omeprazole, a proton pump inhibitor, which inhibits the secretion of acid in the stomach and domperidone, a dopamine antagonist which works as an upper gastrointestinal prokinetic agent. It is useful in the treatment of
Gastroesophageal reflux disease (GERD), and
Dyspepsia caused by gastroparesis and gastroesophageal reflux.
Adults:
The usually recommended dose is one capsule of Enteric Coated Omeprazole and Domperidone SR Capsules once daily before meal.
Elderly:
No dosage adjustment is required.
Pediatric use:
Safety and efficacy have not been established.
Renal and hepatic impairment:
No dosage adjustment is required in patients with renal and hepatic impairment.
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