Osteoporotic Fracture Risk and Dietary Habits

<h2 id="background">Background</h2><ul><li>Exercise, alcohol use, and smoking affect osteoporotic fracture risk, but the impact of eating patterns like breakfast skipping and late dinners on bone fractures remains unclear.</li></ul><h2 id="objective">Objective</h2><ul><li>To investigate how lifestyle factors, particularly dietary habits, relate to osteoporotic fracture risk.</li></ul><h2 id="methods">Methods</h2><ul><li>We analyzed adults ≥ 20 years using Japanese health checkup questionnaires linked to the DeSC claims database.&nbsp;</li><li>Primary outcome was osteoporotic fractures(hip, wrist, spine, upper arm).</li><li>Cox regression models calculated hazard ratios for lifestyle factors versus fracture risk, controlling for known risk factors.</li></ul><h2 id="results">Results</h2><ul><li>Among 927,130 participants(median follow-up: 2.6 years), 28,196 major osteoporotic fractures occurred (incidence rate: 10.8 per 1000 person-years).</li><li>Table 1 shows the adjusted hazard ratios (aHR) and statisfical significance for Lifestyle Factors</li></ul><figure class="image"><img style="aspect-ratio:1147/574;" src="https://cdn.megawecare.com/GHBY/Internal-Images/Adjusted%20Hazard%20Ratios%20for%20Lifestyle%20Factors.webp" alt="Adjusted Hazard Ratios for Lifestyle Factors" width="1147" height="574"></figure><ul><li>Both poor dietary habits consistently affected hip, vertebral, and humeral fractures.</li><li><strong>Combined Dietary Habits Analysis: Compared to "skipping breakfast(—) + late dinner (—)" reference group:</strong></li><li>Late dinner only: aHR 1.09 (1.05-1.13)</li><li>Breakfast skipping only: aHR 1.20 (1.13-1.27)</li><li>Both habits combined: aHR 1.23 (1.13-1.34)</li></ul><h2 id="conclusion" data-section="conclusion">Conclusion</h2><p>This first large-scale study demonstrates that skipping breakfast and late dinner timing independently increase osteoporotic fracture risk, with additive effects when combined.</p>

Diabetes Update 2025   Issue 5 1

<ul><li><a href="#background">Background</a></li><li><a href="#objective">Objective</a></li><li><a href="#methods">Methods</a></li><li><a href="#results">Results</a></li><li><a href="#conclusion">Conclusion</a></li></ul>

Osteoporotic Fracture Risk and Dietary Habits

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